Cytonics is a privately held biotechnology company specializing in the development of diagnostics and therapeutics for osteoarthritis (OA), a disease of the joints that renders the afflicted immobile and in constant pain. Our first product was a biomarker assay for the detection of cartilage degradation products in damaged joints and the spine. This discovery led to the development of our first-generation therapy – a medical devices (510K) that leverages a naturally occuring blood proteing called A2M (alpha-2-macroglobulin) to halt the progression of osteoarthritis and shift the joint into an anabolic, restorative state.
Over 10,000 patients have been successfully treated with our first generation therapy, the “Autologous Protease Inhibitor Concentrate” (APIC) device, to date, cementing Cytonics as a leader in regenerative medicine research and development. The clinical and commercial success of APIC is the basis for our ongoing clinical development, and serves as a critical de-risking element for our entire R&D platform.
Now, we are working on a novel biologic treatment for osteoarthritis that may be the first and only disease-modifying therapy for the disease. This drug, dubbed “CYT-108,” is a variant of the natural A2M utilized in the APIC therapy. CYT-108 has completed Phase 1 clinical trials and is ready for Phase 2 development in 2026-2027.
For the People, By the People
We have raised over $30M from private equity and retail investors, with over $25M coming from everyday “Main Street” investors via equity crowdfunding. Cytonics has pioneered this investor first approach by eliminating Venture Capital from the equation and remaining independent of Big Pharma. With over 7,500 shareholders at our backs, we have demonstrated how the democratization of investing can lead to the democratization of drug development. This paradigm completely upends the traditional biotech industry by allowing individuals to decide what drug development programs advance by voting with their dollar.
The National Institute of Health also supported our research and awarded the company a prestigious $1.8M SBIR grant.
You can learn more about becoming a shareholder here: invest.cytonics.com
Get in touch with our CEO, Joey Bose: joey.bose@cytonics.com
