The Cytonics Autologous Platelet Integrated Concentration (“APIC”) System is indicated for the rapid preparation of autologous platelet rich plasma from a small sample of blood at the patient’s point of care. The platelet rich plasma is mixed with autograft and/or allograft bone prior to application to a bony defect for improving bone graft handling characteristics.
The Autologous Platelet Integrated Concentration (“APIC”) System consists of a centrifuge, a pump, and a disposable processing kit for the preparation of platelet rich plasma (“PRP”). The disposable processing kit contains 3 centrifuge tubes, one sterile filter, one concentration bag, connection tubing, one waste bag, and other sterile and non-sterile, single use, disposable accessories that aid in blood collection, preparation and administration of the PRP. The disposable processing kit must be used in conjunction with the APIC System centrifuge and pump.
The APIC System separates and concentrates platelets from a volume of a patient’s own blood. The patient’s blood is drawn via IV catheter into syringes that are preloaded with anticoagulant citrate dextrose solution A (“ACD-A”). The ACD-A is provided separately and not as part of the disposable processing kit. The blood is then transferred to centrifugation tubes and centrifuged for 4 minutes. The plasma above the buffy coat is transferred to the concentration bag by use of a sterile syringe. The pump circulates the plasma through a filter for 20 minutes. Upon completion of the filtration cycle, the APIC can be drawn from the concentration bag into a syringe and provided for mixing as needed for clinical administration with autograft or allograft bone.
APIC PROCESS OVERVIEW