Clinical Need


In the U.S., over 30 million people are treated for back pain every year, and osteoarthritis (OA) affects nearly 27 million people. Back pain is the #1 cause of missed work and the #1 healthcare expense in our country. Joint pain and OA account for millions of doctor office visits each year, and are rapidly rising as the average life expectancy increases. In all, musculoskeletal disease burdens our nation with human suffering, lost productivity, missed work, and excessive medical expenses.

Cytonics has discovered a unique “bio-marker” that can assist physicians in improving patient outcomes by pinpointing the source of orthopedic pain. Many patients have “normal” looking anatomy following a traumatic injury even though degenerative enzymes may be at work causing pain and slowly destroying their joints. Additionally, patients often have non-painful abnormalities that are indistinguishable from painful conditions. This makes it difficult for surgeons to diagnosis the source of pain and to make decisions on the best course of treatment. The limitations of MRI often lead to misdiagnosis and ineffective treatment, leaving patients to continue to suffer in pain following treatment, despite the best intentions of their physicians.

Research has shown that an inflammatory cascade of proteins causes back and joint pain. Our FACT assay detects a unique bio-marker (FAC) in this cascade allowing physicians to identify and treat the source of pain.

Cytonics is also developing a range of therapeutic products for the treatment of painful osteoarthritis, back, and joint pain.